Waldenström Macroglobulinemia

What Is It?

Waldenström macroglobulinemia (WM) is a rare, slow-growing cancer. It is a form of non-Hodgkin lymphoma. WM is also known as lymphoplasmacytic lymphoma.

WM begins in the immune system. It starts in white blood cells called B lymphocytes (B cells). B cells play a key role in the body's immune system. Some B cells develop into plasma cells. Plasma cells make antibodies (also called immunoglobulins). Antibodies help the body attack bacteria, viruses, and other foreign substances.

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