Heartburn medications and the heart
Ask the doctor
However, there are many other causes for heart disease that were difficult to completely account for in this observational study, such as smoking, obesity, and dietary habits. These same factors are associated with heartburn. So what explains the extra heart attacks—the lifestyle that causes both heartburn and heart attacks, or the PPI that people with heartburn take? Only a randomized, placebo-controlled clinical trial can sort out such cause-and-effect relationships.
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