Heart Health
Niacin + a statin does not add up to benefit
In 2011, federal health officials ended an important government-funded clinical trial designed to test whether taking niacin in addition to a cholesterol-lowering statin might do more to lower heart attack and stroke risk than just taking a statin alone. Interim data indicated that the niacin had no benefit and may have been associated with a small, unexplained increase in stroke risk.
The notion of adding niacin to statins came about for several reasons. Statins do a terrific job of cranking down LDL levels, but they're not big HDL boosters. Studies have shown that increasing HDL while taking a statin might lower cardiovascular risk further. And pharmaceutical companies are looking for new products, especially now that the patents on their brand-name statins, like Lipitor (atorvastatin), have expired.
To continue reading this article, you must log in.
Subscribe to Harvard Health Online for immediate access to health news and information from Harvard Medical School.
- Research health conditions
- Check your symptoms
- Prepare for a doctor's visit or test
- Find the best treatments and procedures for you
- Explore options for better nutrition and exercise
I'd like to receive access to Harvard Health Online for only $4.99 a month.
Sign Me UpAlready a member? Login ».
Disclaimer:
As a service to our readers, Harvard Health Publishing provides access to our library of archived content. Please note the date of last review or update on all articles.
No content on this site, regardless of date, should ever be used as a substitute for direct medical advice from your doctor or other qualified clinician.