By the way, doctor: How much Imitrex is too much?
In general, people aren't supposed to take sumatriptan more than four times a month, and the maximum dose per episode is 200 milligrams. The concern about overusing the triptans comes partly from the possibility that by repeatedly narrowing the blood vessels in the head and chest the drugs might increase stroke and heart attack risk. Although they tend to home in on cranial blood vessels, the triptans also manage to find receptors on the coronary arteries and, very occasionally, can cause chest pain that resembles angina. Yet large studies haven't shown an increase in the number of strokes or heart attacks among people taking the triptans, so the worry may be a bit theoretical.
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