Ask the doctor: Combining painkillers: What you should know.
Is it okay to take both aspirin and ibuprofen therapies?One other thing. Taking ibuprofen or naproxen can reduce the heart-protective effect of aspirin—particularly if taken within two hours of taking aspirin. So if your doctor says you need ibuprofen or naproxen for pain, take it at least two hours after you take the aspirin.
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