Staying Healthy

Do genes or lifestyle determine your health?

Ask the doctor

By , Editor in Chief, Harvard Health Letter; Editorial Advisory Board Member, Harvard Health Publishing
Colorful illustration meant to represent a strand of DNA.Q. What's more important in determining my health: my genes or my lifestyle?

For the rare individuals who live to be 100 or older (centenarians), genes appear to be the dominant force in determining longevity. For example, some centenarians are smokers, but they have genes that allow them to overcome smoking's adverse effects. As you might expect, scientists are trying to identify the protective genes that centenarians have.

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About the Author

photo of Anthony L. Komaroff, MD

Anthony L. Komaroff, MD, Editor in Chief, Harvard Health Letter; Editorial Advisory Board Member, Harvard Health Publishing

Dr. Anthony L. Komaroff is the Steven P. SimcoxPatrick A. Clifford/James H. Higby Distinguished Professor of Medicine at Harvard Medical School, senior physician at Brigham and Women’s Hospital in Boston, and editor in chief of the … See Full Bio
View all posts by Anthony L. Komaroff, MD

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