Cholesterol Archive

People with elevated LDL cholesterol values may be able to reduce their LDL levels by eating more foods that are rich in fiber and lower in saturated fats. High-fiber foods include whole grains, beans, nuts, vegetables, and fruits. Saturated fats are found mainly in meat, cheese, and other high-fat dairy products such as butter, half and half, and ice cream.

Over the past decade, nutrition experts have shifted away from recommending a low-fat diet to focusing more on an overall healthy dietary pattern. This eating style, which includes lots of plant-based foods, is naturally low in saturated fats. Found mainly in meat and dairy products, saturated fat can boost levels of harmful LDL cholesterol, a key contributor to heart disease. Cutting back on all types of fat does not necessarily translate into a diet that lowers cardiovascular risk. The plant-centric Mediterranean eating pattern, which is rich in healthy unsaturated fats found in nuts, seeds, and olives, has the best evidence for lowering heart disease risk.

In people with obesity, a high-dose weekly injection of the diabetes drug semaglutide caused a 15% weight loss and improved other heart-related risk factors. Semaglutide works by mimicking a substance called GLP-1, which is made naturally by the gut and the brain. It prods the pancreas to release insulin when blood sugar rises too high, reduces appetite, and makes people feel full following a meal.

Studies show that people who regularly adhere to the Mediterranean diet lower their risk of cardiovascular disease, many types of cancer, and cognitive decline with age. But it’s possible that this healthy diet can be made even healthier. New research suggests that making the diet "greener" by boosting amounts of dark green vegetables, green tea, and plant proteins high in the micronutrients known as polyphenols offers even greater benefits.

For decades, high intake of fat was thought to cause weight gain, heart disease, and maybe even cancer. The solution? Go low-fat, which often meant consuming more carbs and more sugar. But nutritionists now suggest people actually need adequate amounts of "good" unsaturated fat, and less "bad" saturated fat, for optimal health. Following popular heart-healthy diets, like the Mediterranean and MIND diets, and making simple dietary changes can help people get adequate amounts of good fats.

A gene editing technique that permanently shuts down a cholesterol-raising protein called PCSK9 is being tested in heart attack survivors with an inherited form of high cholesterol. The one-time infusion contains tiny particles that contain the editing tools, which travel through the blood to the liver and changes the cells that produce the protein. If early data show the treatment to be safe and effective, the therapy potentially could be used in people who have "garden variety" high cholesterol.

A coronary artery calcium scan (often called a calcium scan) uses a special type of CT scan to look for calcium deposits in the lining of the heart's arteries. The results can help people decide whether to start taking a statin.

Coffee drinking has been linked to a lower risk of dying of heart disease. Coffee contains potent anti-inflammatory substances called polyphenols that may improve blood sugar control and help blood vessels contract and relax. Although the caffeine in coffee may help people control their weight, it can trigger a short-term rise in blood pressure and heart rate. Filtered coffee, which removes substances that may raise LDL (bad) cholesterol, appears to be a better option than unfiltered coffee.

Nuts contain healthy unsaturated fats, protein, and important nutrients like potassium, and there is ample evidence that eating nuts regularly helps protect against heart disease.