Depression Archive

Most people experience some degree of decreased memory as they get older, but memory performance is also affected by mood and sleep quality, and these are factors that can be controlled and improved.

This age-old relaxation method can bring health benefits, and there are many tools to help get you started.

These days it seems like there's an app for almost everything you can do for your health, from tracking your diet and exercise to charting your sleep patterns. So, it's no surprise that there's been a surge in apps to help with meditation, an ancient practice designed to help you focus inward to promote relaxation.

In fact, Apple designated "self-care" — a category that includes meditation, mindfulness, and general wellness — as the 2018 "app trend of the year." This mirrors growing interest in meditation as an overall health strategy, a movement likely driven by a growing body of research showing potential health benefits from the practice.

Running for 15 minutes a day or walking for an hour reduces the risk of major depression, according to a recent study.

It may be possible to outrun depression, according to a study published online January 23 by JAMA Psychiatry.

"We saw a 26% decrease in odds for becoming depressed for each major increase in objectively measured physical activity," says study author Karmel Choi, a clinical and research fellow at the Harvard T.H. Chan School of Public Health. "This increase in physical activity is what you might see on your activity tracker if you replaced 15 minutes of sitting with 15 minutes of running, or one hour of sitting with one hour of moderate activity like brisk walking."

ARCHIVED CONTENT: As a service to our readers, Harvard Health Publishing provides access to our library of archived content. Please note the date each article was posted or last reviewed. No content on this site, regardless of date, should ever be used as a substitute for direct medical advice from your doctor or other qualified clinician. 

Q. Does the acne drug, isotretinoin (Accutane), cause depression and suicide, or are psychiatric risks from the Accutane side effects exaggerated?

Dealing with the emotional effects from a physical setback can be a challenge. These three strategies can help.

The physical repercussions of a major health issue, like surgery, an injury, or a heart attack, are tough enough without having to also confront the stress, anxiety, and depression that often accompanies it. Yet managing your mental health is just as important as your physical health when it comes to making a full recovery.

"There is no question that your state of mind can dictate how quickly you can return from a physical setback," says Dr. Jeff Huffman, director of the cardiac psychiatry research program at Harvard-affiliated Massachusetts General Hospital.

Stress and depression may lead to new health issues or intensify the symptoms of existing conditions.

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We tend to think of grieving as an emotional experience, and it is — fraught with intense sadness, profound loss, and psychological pain. But grief has a physical side that sets us up for a number of health risks. "Most of these side effects are the result of emotional distress responses," explains Dr. Maureen Malin, a geriatric psychiatrist with Harvard-affiliated McLean Hospital. Whether you're grieving the loss of a loved one, a job, a home, or a beloved pet, it's important to understand how the process puts your health in jeopardy.

Stress and grief

Grieving takes a toll on the body in the form of stress. "That affects the whole body and all organ systems, and especially the immune system," Dr. Malin says. Evidence suggests that immune cell function falls and inflammatory responses rise in people who are grieving. That may be why people often get sick more often and use more health care resources during this period.

These conditions are associated with a higher risk.

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Most men are familiar with the common strategies to reduce their heart disease risk: keep cholesterol in check, manage high blood pressure, follow a heart-healthy diet, and perform regular exercise. But there may be other preventive steps you can take.

"Some age-related conditions can further increase your risk without you knowing it, which is why it's important to be mindful about all aspects of your health," says Dr. Michael Gavin, a cardiologist with Harvard-affiliated Beth Israel Deaconess Medical Center. "Fortunately, once they are recognized, these other risk factors can be addressed and managed."

Common mental health disorders are linked to a higher risk of heart attack and stroke. Learn to spot the warning signs.

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Heart disease and mental health issues are both common. So it's not surprising that these problems often occur together. But are people with depression or anxiety more prone to developing cardiovascular disease?

Teasing out the answer to that question has proved tricky. Some factors known to contribute to a higher risk of heart disease (for example, an unhealthy diet, lack of exercise, and smoking) are also common in people with mental health issues. Now, new research that adjusts for those potentially confounding factors suggests the answer is yes.

Ketamine offers a new option for people with stubborn depression that doesn't respond to other medications.

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Many people know of ketamine as a hallucinogenic and addictive street drug, which, when abused, can put people in medical peril. But today, doctors are increasingly looking to ketamine as a potentially lifesaving treatment for people with severe, treatment-resistant depression, who may be at high risk for suicide.

"Ketamine has been shown to be effective in people who have not responded to antidepressant treatment," says Dr. Cristina Cusin, an assistant professor of psychiatry at Harvard Medical School. The fast-acting treatment has shown promise — sometimes improving depressive symptoms within hours of the first intravenous treatment.

News briefs

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We're learning more about the link between weight gain and several major classes of antidepressants, such as selective serotonin reuptake inhibitors (SSRIs), like sertraline (Zoloft), and tricyclic antidepressants, such as amitriptyline (Elavil). Research has shown that putting on pounds is a possible short-term side effect of the medications. But a study published May 23, 2018, in The BMJ suggests that antidepressants are also associated with sustained weight gain. Researchers analyzed the health information of more than 300,000 people in the United Kingdom (average age 51) who'd had their weight and body mass index measured at doctor appointments between 2004 and 2014. About 18% had been prescribed antidepressants. During the study period, people who took antidepressants had a 21% higher risk for a 5% or greater weight gain, compared with people who didn't take antidepressants. The risk peaked in the second and third years. There was no evidence of weight gain after seven years. The study was observational and didn't prove that antidepressants cause weight gain. But researchers hope the findings will encourage people to talk to their doctors about weight gain as a possible side effect of antidepressants, and plan for potential and even delayed weight gain if they're using the medications.