Diseases & Conditions Archive

Ask the doctor

Q. I've taken blood pressure medicines every morning for many years, and they keep my pressure under control. Recently, my doctor recommended taking them at bedtime, instead. Does that make sense?

A. It actually does make sense — based on recent research. For many years, there have been at least three theoretical reasons for taking blood pressure medicines before bedtime. First, a body system that strongly affects blood pressure, called the renin-angiotensin system, has its peak activity during sleep. Second, circadian rhythms cause differences in the body chemistry at night compared with daytime. Third, most heart attacks occur in the morning, before medicines taken in the morning have a chance to "kick in."

Ask the doctors

Q. I recently started experiencing a lot of pain in my hand from osteoarthritis. Can I reverse this condition?

A. You can't reverse osteoarthritis, but there are things you can do to manage your pain and improve your symptoms. Osteoarthritis occurs when the protective cartilage that acts as cushioning between your bones starts to fray and wear down over time. Eventually this enables the bones to rub together, which causes the pain you are experiencing as well as swelling and stiffness that makes it difficult to move your hand freely. Typically, when you have arthritis, the pain and symptoms will be worse at some times than at others. You may experience a flare-up one day and feel better the next. To help reduce the discomfort of a flare-up, talk to your doctor about medication to relieve pain. She or he may recommend an over-the-counter pain reliever. Some people also get symptom relief using a topical pain reliever that is rubbed into the skin. Other strategies that can ease pain are splints or braces, heat or cold therapy, activity modification, and exercises or physical therapy to increase flexibility and strengthen your hand muscles.

What is the test?

Chorionic villi are small branching structures on one side of the placenta. They anchor the placenta to the wall of the uterus, almost like the roots of a plant. They have another root-like function, which is to absorb nutrients from the mother's blood in the lining of her uterus, and to deliver these to the umbilical cord. These structures contain cells from the developing fetus. A test that removes a sample of these cells through a needle is called chorionic villus sampling (CVS).

CVS answers many of the same questions as amniocentesis about diseases that the baby might have. Diseases that can be diagnosed with CVS include Tay-Sachs, sickle cell anemia, cystic fibrosis, thalassemia, and Down syndrome. (Rh incompatibility and neural tube defects, however, can be diagnosed only through amniocentesis.) CVS can be done earlier in pregnancy than amniocentesis and can be done when there is not enough amniotic fluid to allow amniocentesis. However, it has some extra risks when compared with amniocentesis.

What Is It?

Squamous cells are small, flat skin cells in the outer layer of skin. When these cells become cancerous, they typically develop into flat or raised, rounded skin tumors. Sometimes the skin around the tumors gets red and swollen.

Most cases of squamous cell carcinoma occur in people who have spent lots of time in the sun—especially those with fair skin and blue eyes. Some cases develop on skin that has been injured or exposed to cancer-causing agents. This type of squamous cell cancer can develop on:

What Is It?

A drooping eyelid is also called ptosis or blepharoptosis. In this condition, the border of the upper eyelid falls to a lower position than normal. In severe cases, the drooping eyelid can cover all or part of the pupil and interfere with vision.

Ptosis can affect one or both eyes. It may be present at birth (congenital ptosis), or it may develop gradually over decades. Sometimes ptosis is an isolated problem that changes a person's appearance without affecting vision or health. In other cases, however, it can be a warning sign that a more serious condition is affecting the muscles, nerves, brain or eye socket. Ptosis that develops over a period of days or hours is more likely to signify a serious medical problem.

What Is It?

Hearing loss is a decrease in the ability to perceive sounds. It can be partial or total, sudden or gradual, temporary or permanent. It can affect one ear or both. In general, the risk of hearing loss increases with age.

Sound enters the ear and strikes the eardrum. This causes the eardrum to vibrate. The eardrum's vibrations are amplified through the middle ear by three tiny bones. Inside the ear, the vibrations are transformed into nerve impulses. These nerve impulses travel to the brain, where they are interpreted as sounds.

What Is It?

Hepatitis is inflammation of the liver. There are several types of hepatitis. The disease has several causes.

One cause of hepatitis is infection. Most cases of infectious hepatitis in the United States are caused by hepatitis A, B or C virus.

What Is It?

Multiple sclerosis (MS) is a neurological illness that affects the brain and spinal cord. Symptoms of the disease be intermittent (they come and go). Or MS can be progressive. This means it worsens over time. 

Nerve cells called neurons send out long "fingers" called axons.  The axons from one neuron send signals to another neuron that may be a long ways away.  A substance called myelin normally is wrapped around the axons. Myelin helps the axon transmit signals from one neuron to another.