Headache Archive

A 2024 analysis of 137 studies involving almost 90,000 people found that older drugs called triptans are more effective at stopping migraine pain in a moment of agony, compared with newer medications such as ditans and gepants.

Migraine can carry a certain stigma that unfairly marks individuals with the condition. A 2024 study suggested that such stigma might be tied to increased disability and reduced quality of life for people struggling with this debilitating disease. To cope with migraine stigma, it helps to talk to a psychologist or join a migraine support group, educate loved ones, and talk to one's boss regarding accommodations needed to cope with migraine on the job.

Antidepressants influence the way brain chemicals regulate mood and other body functions and behaviors. Examples include selective serotonin reuptake inhibitors, such as fluoxetine (Prozac) and citalopram (Celexa); and serotonin and norepinephrine reuptake inhibitors, such as venlafaxine (Effexor) and duloxetine (Cymbalta). Although the medications are commonly used to treat depression, sometimes they are used to treat other conditions such as insomnia, headaches, gynecological pain, or nerve pain.

Migraines and cardiovascular disease share certain common features, including changes in blood vessels, blood flow, and inflammation. Migraine with aura is linked to an increased risk of stroke, and common migraine drugs called triptans are linked to a higher risk of stroke and heart attack in people at risk for cardiovascular disease. Although both of these risks are extremely small, migraine sufferers with heart-related risks should seek out a personalized approach for treatment and know the warning signs of a stroke.

A 2024 study suggests that younger women with migraines and early menopause symptoms such as hot flashes and night sweats may have higher cardiovascular risks at midlife.

The pain reliever acetaminophen is safe when used correctly, but people can become very ill or die if they take too much.

At any given time, up to 15 million people in the United States are believed to have brain aneurysms. Most of the time, brain aneurysms don't cause any problems. However, they do rupture in about 30,000 people each year. When an aneurysm leaks or bursts, it increases pressure in the skull, causing damage, swelling, fluid buildup, and sudden, severe head pain unlike any other headache. It's a life-threatening medical emergency and needs to be investigated at an emergency department immediately.

Many medications claim to relieve migraine pain, but some are more helpful than others. In a large study looking at real-world data on 25 drugs, migraine sufferers rated the most and least helpful options.