Heart Attack Archive

Articles

Keeping tabs on triglycerides

People monitor their cholesterol levels, but they should also watch their triglycerides.

Most people have heard of the two main kinds of cholesterol: the "good" HDL and the "bad" LDL. Doctors focus on controlling LDL, as high levels can lead to a buildup of fatty deposits in the arteries and block blood flow, which can trigger a heart attack or stroke.

A blood test called a lipid profile measures your HDL, LDL, and total cholesterol levels. But within that test is another number you should not ignore: your triglyceride levels.

FDA approves fish oil-based drug for heart attack and stroke prevention

Research we're watching

Late in 2019, the FDA approved a new use for icosapent ethyl (Vascepa), a drug that is a highly purified form of eicosapentaenoic acid (EPA), an omega-3 fatty acid found in fish.

The drug was originally approved in 2012 for treating people with very high levels of triglycerides, a type of fat in the blood. Now, icosapent ethyl is approved for people with triglyceride levels greater than or equal to 150 milligrams per deciliter who also have an elevated risk of cardiovascular disease despite taking the highest tolerable dose of a cholesterol-lowering statin. A large trial found that the drug decreases the risk of heart attack, stroke, and death from cardiac causes by 26% when compared with a placebo.

Biotin supplements may interfere with test to diagnose heart attack

Research we're watching

Taking supplements that contain high levels of biotin (vitamin B7) can lead to falsely low results on a blood test used to detect heart attacks, according to an FDA warning issued late last year.

For adults, the recommended dietary allowance (RDA) for biotin is 0.03 milligrams (mg), which is easily obtained through a healthy, varied diet. Many multivitamins and prenatal vitamins contain far more biotin than the RDA. And some supplements — particularly those marketed to improve hair, nails, and skin — contain 20 mg, or nearly 650 times the RDA.

Gout drug may help prevent repeat heart attacks

Research we're watching

A drug long used to treat a painful form of arthritis called gout may also benefit heart attack survivors, according to a new study.

Derived from the autumn crocus, colchicine (Colcrys, Mitigare) helps to ease the joint inflammation and pain that characterize gout. Because mounting evidence suggests that inflammation plays a role in heart disease, researchers have tested various anti-inflammatory drugs in heart patients. The latest study, published online Nov. 16, 2019, by The New England Journal of Medicine, tested colchicine against a placebo in 4,745 people who had experienced a heart attack within the previous month. All the participants also took standard drugs to treat heart disease, including statins, aspirin, and other clot-preventing drugs.

Don’t stress about heart health

Chronic stress is associated with an increased risk of heart disease, heart attacks, and strokes. These strategies can help you manage it.

People often complain about stress, but it's actually a natural reaction with an essential purpose.

When the body senses danger, it starts its fight-or-flight response. Your nervous system releases hormones like adrenaline and cortisol, which jolt the body into a protective mode. Your heart pounds faster, muscles tighten, blood pressure rises, breathing quickens, and your senses sharpen.

Is nighttime the right time for blood pressure drugs?

Taking these medications at bedtime rather than in the morning may make them more effective.

Many people take their medications as part of their morning ritual, along with a cup of coffee and the daily newspaper. But for blood pressure drugs, evening may be a better option. Last year, a large study found that taking blood pressure drugs before bed may lower the risk of serious heart-related complications more than taking the drugs in the morning (see "Benefits of bedtime blood pressure dosing").

The concept of chronotherapy, or adjusting medication dosing to a specific time of day, isn't new. There's not a great deal of evidence to support the practice with cardiovascular drugs, but it makes sense, says Dr. Naomi Fisher, director of the Hypertension Specialty Clinic at Harvard-affiliated Brigham and Women's Hospital.

How better blood pressure control may benefit the brain

Research we're watching

Treating high blood pressure may do more than prevent heart attacks and strokes. In older adults, intensive blood pressure lowering may also conserve brain function, according to a new study.

Published online Oct. 14, 2019, by the journal Circulation, the study included 199 adults ages 75 and older, all with a systolic blood pressure value (the first number in a reading) of 150 or higher. Their brain scans also showed lesions in the brain's white matter, which contains nerve fibers that send signals from one part of the brain to another. The lesions, which reflect damaged small blood vessels, have been linked to a propensity for thinking and memory problems. About two-thirds of people over age 75 have white matter lesions, as do most people over age 90.

Omega-3 supplements may improve heart health

In the journals

Research continues to explore the possible benefits of omega-3 fish oil supplements, especially for heart health, and a recent review of existing data suggests they may protect against heart attack and coronary artery disease.

Researchers from Harvard's T.H. Chan School of Public Health and Brigham and Women's Hospital examined 13 trials, involving almost 128,000 people, to look for any association between omega-3 supplements and the risk of heart attacks, strokes, coronary artery disease, and death from cardiovascular disease. Their results were published online Sept. 30, 2019, by the Journal of the American Heart Association.

Hot flashes and heart health

This symptom is common in menopause, but frequent or persistent episodes could be a sign of higher risk for heart attack or stroke.

Researchers have begun to pay more attention to cardiovascular risk factors that are unique to women, such as early menopause (before age 40) and certain pregnancy complications. Recently they turned their attention to a common menopausal symptom that affects up to 85% of women: hot flashes.

Study results presented in September 2019 to the North American Menopause Society from the Study of Women's Health Across the Nation (SWAN) found that women who experience frequent or persistent hot flashes may be more likely than women who don't to experience a heart attack or stroke or other serious cardiovascular problems. (Researchers defined "frequent" hot flashes as having them six or more days in the previous two-week period. Women with "persistent" hot flashes reported those frequent hot flashes at 25% or more of study visits.)

Advice about taking aspirin and statins after age 75

These drugs are mainstays for preventing heart disease. Are they safe and effective in older people?

Low-dose aspirin and statins are both common, inexpensive drugs that help prevent the two root causes of most heart attacks — blood clots and cholesterol-laden plaque clogging the arteries of the heart. In recent years, a number of studies have helped experts refine their advice as to who should or should not take these medications.

However, evidence-based advice for people in their mid-70s and beyond is a bit harder to come by. Historically, most drug trials have included only a small proportion of people 75 and older, in part because there are fewer people in that age demographic. Also, older people tend to have other chronic health conditions. As such, they may be more prone to drug side effects, making doctors reluctant to enroll them in clinical trials.

Free Healthbeat Signup

Get the latest in health news delivered to your inbox!

Sign Up
Harvard Health Publishing Logo

Thanks for visiting. Don't miss your FREE gift.

The Best Diets for Cognitive Fitness, is yours absolutely FREE when you sign up to receive Health Alerts from Harvard Medical School

Sign up to get tips for living a healthy lifestyle, with ways to fight inflammation and improve cognitive health, plus the latest advances in preventative medicine, diet and exercise, pain relief, blood pressure and cholesterol management, and more.

Harvard Health Publishing Logo

Stay on top of latest health news from Harvard Medical School.

Plus, get a FREE copy of the Best Diets for Cognitive Fitness.

Harvard Health Publishing Logo

Stay on top of latest health news from Harvard Medical School.

Plus, get a FREE copy of the Best Diets for Cognitive Fitness.