Heart Disease Archive

A polygenic risk score for heart disease is based on an analysis of more than three million common DNA variants and is expressed as a percentile. People can have zero, one, or two copies of any variant, each of which may either raise or lower the risk of coronary artery disease. Many of these variants occur in genes known to affect heart disease, such as those related to cholesterol, blood pressure, and blood clotting. Others aren't well understood and may provide targets for future research, potentially fueling new drug discovery efforts. For now, the potential benefits of this test are greatest for people under 50.

A 2023 study suggests eating enough of six categories of food common in popular heart-health diets is associated with a lower risk of cardiovascular disease, including heart attacks and strokes. The six groups are fruits, vegetables, legumes, nuts, fish, and dairy products.

Men often confront obstacles that keep them from managing heart disease or lowering their risk for it. Harvard cardiologists share the advice they give patients who face challenges in the areas of weight loss, medication management, exercise, and diet. These include thinking about their future health goals, monitoring blood pressure, scheduling workouts, joining group weight-loss groups, and learning portion control for meals.

Troponins, which are proteins found in heart muscle cells, are released in the bloodstream during a heart attack. Other conditions, such heart muscle inflammation and chronic kidney disease, can also cause troponin levels to rise.

Naps can be healthy for adults who need to catch up on sleep or work odd hours, but they can also make it more difficult to sleep at night and be a sign of a sleep disorder. Naps should be short and limited to the early afternoon to prevent them from interfering with nighttime sleep. People who have the urge to nap daily should consider whether they need to improve their nighttime sleep habits.

People with autoimmune diseases may be up to three times more likely to develop cardiovascular disease than people without an autoimmune disease. Among the most common autoimmune diseases are rheumatoid arthritis, psoriasis, and lupus. Awareness of this elevated risk is especially important because autoimmune disease typically strikes when people are in their 20s or 30s. In turn, heart problems may develop up to a decade earlier than in people without an autoimmune disease. A calcium scan, which detects early signs of atherosclerosis, can help assess a person's risk and guide treatment advice.

Pregnancy and reproductive complications, including high blood pressure, diabetes, pre-eclampsia, infertility, and stillbirth, are linked with higher cardiovascular risks in affected women many years later. Such complications affect 5% to 10% of pregnancies and are rising as obesity rates increase and more women postpone pregnancy. Ongoing preventive care and screenings are crucial for women who experienced pregnancy complications to monitor blood pressure, cholesterol, and blood sugar levels and treat any irregularities aggressively.

A 2023 review of 70 studies found that both unprocessed and processed red meat are linked to higher risks of cardiovascular disease and diabetes, with no apparent difference in risk between men and women.