Heart Health Archive

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New guidelines and a novel diabetes drug point to new treatment approaches.

When it comes to the cardiovascular dangers from diabetes, the statistics are pretty disheartening: about two-thirds of people with type 2 diabetes ultimately die from heart disease or a stroke. But there's progress afoot. Recently updated guidelines and a novel diabetes drug with proven heart benefits offer promise for making a dent in that dire statistic. And in a nod to the importance of early detection, the U.S. Preventive Services Task Force recently recommended that adults ages 40 to 70 who are overweight be screened for diabetes (see "Diabetes screening tests").

To use the online heart age calculator, the only numbers you need are your height, weight, and blood pressure reading.

Most Americans are not as young at heart as they might like to believe. More than three in four adults have a "heart age" that's greater than their chronological age, according to federal health officials.

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Research we're watching

Drinking as little as one sugar-sweetened beverage a day is linked to a slightly greater risk of high blood pressure, a new analysis suggests.

Researchers pooled findings from six studies that included a total of more than 240,000 people. They found a 12% higher risk of high blood pressure among people who drank one or more sugary drinks daily compared with those who drank none. Serving sizes of the beverages varied from 7 to 12 ounces among the different studies.

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Research we're watching

Women who have heart attacks before age 60 may be less likely to receive a lifesaving procedure to restore blood flow to the heart (an angioplasty plus a stent) than men in that age group, according to a study in the Oct. 26, 2015, Journal of the American College of Cardiology. (Stents are tiny mesh tubes that help keep arteries open.)

Data for the study came from a nationwide sample of more than 630,000 people ages 18 to 59 who had heart attacks. Younger women also were more likely to die in the hospital compared with younger men (4.5% versus 3%, respectively). However, men may be more likely to die before reaching the hospital than women, which may partly explain that difference, the researchers say.

Research we're watching

For people who take anti-clotting drugs such as dabigatran (Pradaxa), one serious downside has been the rare but dangerous risk of uncontrolled bleeding in the event of an accident or urgently needed surgery. But in October, the FDA approved idarucizumab (Praxbind), a drug that quickly reverses the effects of dabigatran. Given by injection into a vein, the drug binds to dabigatran and neutralizes its effect, allowing the blood to clot normally.

Dabigatran was approved in 2010 to prevent strokes (most of which are caused by blood clots in the brain) in people with atrial fibrillation. It's also prescribed to prevent and treat venous thromboembolism. Because idarucizumab works specifically on dabigatran, it can't be used as an antidote for similar anti-clotting medications, which include rivaroxaban (Xarelto), apixaban (Eliquis), and edoxaban (Savaysa). However, an antidote that works on these drugs is under development, with approval expected within the next year or so.

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Smartphone apps encourage you to take an active role in monitoring and boosting health.

When it comes to healthy hearts, technology is playing a greater role than ever, and not just in the doctor's office. Now nearly anyone can use computer programs designed to improve heart health, thanks to downloadable applications (apps) for smartphones, tablets, and home computers. They're part of a trend known as mobile health or mhealth. "In general, health apps can provide very valuable information, as long as you understand their limitations," says Dr. Randall Zusman, a cardiologist with the Corrigan-Minehan Heart Center at Harvard-affiliated Massachusetts General Hospital and a Harvard Medical School associate professor.

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News briefs

Initial results of a large national clinical trial suggest that being more aggressive in treating high blood pressure may save lives. Results of the Systolic Blood Pressure Intervention Trial (SPRINT) aren't yet published, so we don't know all of the details. But from information released by the National Institutes of Health (NIH) in September, it appears that aiming for a systolic (top) blood pressure reading of less than 120 mm Hg may reduce the risk of heart attacks, strokes, and heart failure by almost a third, and reduce the overall death rate by 25%. Researchers came to this conclusion after following more than 9,000 middle-aged and older adults with high blood pressure for several years. Half of the participants took an average of two medications and set a target systolic blood pressure of less than 140 mm Hg, the current recommended number. The other half took an average of three medications and aimed for a systolic blood pressure of less than 120 mm Hg. The results in the lower-target group were so impressive that NIH stopped the study early to share the news. Does this mean you should add more pills to your blood pressure treatment? "Not necessarily, because there may be more drug side effects. But if you're aiming for a lower number, I think it will be critical to rely on lifestyle modification, such as stress reduction, diet, salt restriction, and exercise, in addition to medication to lower blood pressure," says Dr. Randall Zusman, a cardiologist and Harvard Medical School associate professor.