Heart Health Archive

Clinical trials are under way using gene therapy to treat inherited cardiovascular conditions, including familial hypercholesterolemia (one form of abnormally high cholesterol), hypertrophic cardiomyopathy (a type of heart muscle disease), and transthyretin amyloid cardiomyopathy (a form of heart failure resulting from amyloid deposits). But challenges remain in developing and delivering these therapies.

People whose spouses have high blood pressure may be more likely to have high blood pressure themselves than people whose spouses do not have the condition, according to a 2023 study.

Many studies suggest that fiber-rich diets may help prevent heart disease. But most Americans eat only about 16 grams of fiber a day-far less than the recommended amounts.

When people with atrial fibrillation sleep poorly, they may be more likely to have an episode of atrial fibrillation the next day, according to a 2023 study.

Indirect evidence suggests that for people with atrial fibrillation who always take apixaban (Eliquis) every 12 hours as prescribed, it may be slightly better than once daily rivaroxaban (Xarelto).

The portfolio diet, which emphasizes foods rich in fiber and healthy fats, helps lower LDL cholesterol. A 2023 study suggests that the more closely people follow the diet, the lower their risk of cardiovascular disease. The diet discourages foods from animal sources and features foods from five main categories, including (1) plant protein such as legumes; (2) nuts and seeds; (3) foods rich in viscous fibers such as oatmeal, eggplant, and berries; (4) plant sterols such as phytosterol-enriched margarine; and (5) monounsaturated fats such as olive and canola oils.

Orthostatic hypotension, a condition that causes blood pressure to drop when a person stands up, can leave people dizzy and lightheaded. It can result from certain medications or health problems and becomes more common with age and frailty. Doctors sometimes worry that intensive blood pressure treatment contributes to the problem, but research suggests the opposite is true. Strategies to cope with symptoms of orthostatic hypotension include drinking plenty of fluids, wearing compression stockings, and taking care when rising from a chair or bed.

The weight-loss drug semaglutide is the first obesity treatment shown to help people live longer and have fewer cardiovascular problems. Developed as a drug for type 2 diabetes, semaglutide was first marketed as Ozempic; a higher-dose version for weight loss is called Wegovy. But because the drug is so popular, it can be hard to find, and it might not be covered by insurance.

Metabolic syndrome is a constellation of interrelated health conditions that significantly increases the risk for heart attacks, strokes, diabetes, and more. A diagnosis requires at least three of the following risk factors: obesity, high blood sugar, high triglycerides, low HDL (good) cholesterol, or high blood pressure. Metabolic syndrome can be reversed if it's recognized. Losing weight is central to reducing many of its features. Lowering elevated blood pressure, blood sugar, and cholesterol levels also plays a major role in reducing the risk for heart disease and stroke.

A significant reduction in salt intake may directly lower blood pressure in even more people than previously believed.