Heart Health Archive

Research we're watching

A unique diabetes drug shows heart-related benefits in people with diabetes who also have recently worsening heart failure or kidney disease, according to two new studies.

The drug, sotagliflozin (Zynquista), belongs to a class of drugs called SGLT2 inhibitors, which cause the kidneys to release more sugar into the urine. The drug is also an SGLT1 inhibitor, meaning it decreases sugar absorption in the intestines. This dual action lowers high blood sugar, the hallmark of diabetes. In people with kidney disease, sotagliflozin lowered the total number of deaths from cardiovascular disease and hospitalizations and urgent visits for heart failure by about 26% compared with a placebo. In a second study, which included people with recently worsening heart failure, those taking the drug had a 33% decrease in those same heart-related measures compared with a placebo.

Research we're watching

Doing vigorous exercise for just 12 minutes triggers changes in blood levels of substances linked to cardiovascular health, new research finds.

The study used data from 411 middle-aged adults from the Framingham Heart Study. Researchers measured levels of 588 substances involved in metabolism (metabolites) in the volunteers' blood before and immediately after 12 minutes of vigorous exercise on an exercise bike.

Your partner's flawed health behaviors may be harming your heart.

It's been said that the longer couples stay together the more they look alike. As it turns out, the resemblance may be more than skin-deep. A study published online Oct. 26, 2020, by JAMA Network Open found that couples' health behavior and heart disease risk factors also look alike — for better or worse.

"We know, even from personal experience, that couples share similar behaviors that can affect health, but it was surprising to find the high levels of shared unhealthy behaviors within couples," says the study's lead author, Dov Shiffman, a senior scientific fellow at the medical testing company Quest Diagnostics.

During waking hours you may feel your heart rate fluctuating, and activity or intense emotions can cause it to spike. But what happens to your heart rate when you sleep? It varies then too, depending on the phase of sleep you are in.

The culture of American medicine has long believed and supported the idea that more early detection and treatment is best. But some testing is costly, invasive and carries needless risks, and some conditions go away on their own. Early detection and treatment can be lifesaving — just not for every health issue.

Regardless of your size or fitness level, exercise has multiple benefits. Almost anything that gets you moving counts, and some activity is always better than none. These suggestions can help you make exercise work for you.

Learn when, how, and why you should keep track of your heartbeat.

Soon after you wake up tomorrow morning, before you even sit up in bed, take your pulse. It's fairly easy if you have a clock or timer nearby (see "Measuring your heart rate"). Known as your resting heart rate, this value ranges from 60 to 100 beats per minute in most adults.

"To get a good sense of your resting heart rate, check it every few mornings over the course of several weeks," advises cardiologist Dr. Aaron Baggish, director of the Cardiovascular Performance Program at Harvard-affiliated Massachusetts General Hospital. It's best to measure your resting heart rate when you've been getting your typical amount of sleep and exercise and aren't feeling ill or dehydrated.

Your cholesterol and other factors linked to cardiovascular health may be influenced by the bacteria in your belly.

The roughly 38 trillion bacteria that dwell deep within your intestines perform many important tasks. Collectively known as the gut microbiota, these microbes help digest food, metabolize medications, and protect you from infectious organisms.

In many ways, your gut microbiota — which weighs about half a pound in total — functions somewhat like a distinct organ in your body. Just as you have a unique genome, you also have a unique gut microbiome, consisting of some eight million genes that control your microbiota. Scientists are still learning how the composition and diversity of the gut microbiome influence the health of the cardiovascular system.

New findings challenge the widespread belief that aggressive blood pressure treatment may trigger a condition linked to fainting and falls.

When doctors treat older people with high blood pressure, they often worry about a condition that causes blood pressure to plummet when a person stands up from a seated or lying position. Known as orthostatic hypotension (hypotension means low blood pressure), it affects as many as one in five people ages 65 and older.

Because orthostatic hypotension can make you feel dizzy or lightheaded after standing, it may lead to fainting and falls — with possibly serious repercussions. This concern leads some doctors to ease up on prescribed blood pressure medications. But a new study suggests that practice actually might do more harm than good.

For people recently diagnosed, taming the heart's rhythm rather than slowing it down may be a better approach.

The heart rhythm disorder known as atrial fibrillation (afib) occurs when the heart's electrical system goes awry. Instead of the heart's natural pacemaker creating a steady beat, the heart's upper chambers (atria) pulsate rapidly — up to hundreds of times per minute. Most of the electrical impulses telling the lower chambers (ventricles) to contract don't get through but many do, triggering a racing, irregular heartbeat that can leave people dizzy, breathless, or fatigued.

Therapies to tackle this common arrhythmia have improved over the years. Now, new findings suggest it may be time to rethink the treatment for people newly diagnosed with afib (see "Afib: Rhythm vs. rate control").