Heart Health Archive

A stent can save your life during a heart attack, but can it help prevent one?

 Image: © jauhari1/Getty Images

An estimated two million people get coronary artery stents every year, and if you have coronary artery disease, there is a good chance your doctor will suggest you get one.

But do you really need it? In 2013, the American Medical Association issued a report that said stents were one of the most highly overused medical interventions.

Research we're watching

Doing easy leg stretches may improve blood flow throughout the body by making the arteries more flexible and able to dilate, according to a small study in the July 1, 2020, Journal of Physiology.

The study included 39 young adults, 27 of whom did passive leg stretches five times a week for 12 weeks, while the other 12 did no stretching. (Passive stretching involves holding a stretch for a set period of time aided by an outside force, such as one's body weight or gravity). Volunteers held the thigh and calf stretches for 45 seconds, followed a 15-second rest. They repeated each set a total of five times.

Research we're watching

A team of scientists have created a tiny heart muscle "pump" using human cells and a three-dimensional bioprinter. The model heart — which was sized to fit inside a mouse's abdominal cavity — may one day prove useful for studying new heart medications and other therapies, they say.

The researchers first tried using heart muscle cells (cardiomyocytes) in the 3D printer, but the cells didn't grow to a sufficient size and volume. So they instead used so-called pluripotent stem cells, which have the ability to transform into different cell types. After printing a chambered structure, they were able to program the stem cells to become cardiomyocytes, which then began to organize and work together. Within about a month, the cells began beating together, similar to a human heart. The research is detailed in a study published July 3, 2020, in the journal Circulation Research.

Research we're watching

A recent study found that nearly one in 10 people who received opioid pain relievers following heart surgery continued to take them for three to six months — a time point when no one should still be experiencing pain from the operation.

The study included nearly 36,000 people with private health insurance who had a coronary artery bypass graft (known as CABG or bypass surgery) or a heart valve replacement between 2003 and 2016. People who were prescribed more than 40 5-mg tablets of oxycodone (Oxycontin, Roxicodone, others) or an equivalent amount of a similar drug were at a much higher risk of prolonged opioid use than people who were prescribed lower doses. Other factors that increased a person's odds of taking opioids long-term included having CABG, being female, or having a history of chronic pain or alcoholism.

Heart attack symptoms can differ between men and women, but not as much as you might think.

Thanks to national campaigns to boost awareness, more people now recognize that heart disease is the leading cause of death in women as well as in men. For both sexes, cardiovascular disease is to blame for one of every three deaths in the United States.

Throughout the country, someone has a heart attack — the most common manifestation of this prevalent disease — about every 40 seconds, on average. Maybe you've heard that women are more likely to have "atypical" heart attack symptoms than men. But what does that really mean? A review article in the May 2020 Journal of the American Heart Association offers some perspective.

In the journals

Age may not be a factor when it comes to who can benefit from statins. A study published online July 7, 2020, by JAMA found that people who started taking the cholesterol-lowering medication in their mid-70s or later had fewer heart-related problems and lived longer than non-users.

Researchers looked at 326,981 mostly male veterans, ages 75 and older, who were free of cardiovascular disease and did not take statins. Over the next 10 years, more than 57,000 began statin therapy.

People who take frequent saunas or hot baths may lower their risk of heart problems. But be cautious if you have low blood pressure.

Soaking in a bathtub or basking in a sauna can be a pleasant way to relax. Done on a regular basis, both habits may also help prevent heart attacks and strokes, according to several studies.

"The high temperatures in a warm tub or sauna cause your blood vessels to dilate, which lowers blood pressure," says Dr. Adolph Hutter, professor of medicine at Harvard Medical School. The volume of blood your heart pumps will also rise, especially in a hot tub. That's a result of the pressure of the water on the body, which increases the heart's workload, he explains.

For monitoring conditions that contribute to heart attack and stroke, virtual doctor visits are much more convenient than in-person appointments. Where is this trend headed?

Virtual doctor visits — when you talk to a physician on a video call instead of during an in-person office exam — have been available in certain places for years. But they never really caught on until the pandemic hit earlier this year. Almost overnight, virtual care became an indispensable tool for managing coronavirus infections and other health conditions during the crisis.

In 2019, virtual visits accounted for fewer than 1% of the appointments at Mass General Brigham, a large health care system founded by Harvard-affiliated Brigham and Women's Hospital and Massachusetts General Hospital (MGH). "But during the peak of the coronavirus surge in Boston, 80% of all visits were done virtually," says Dr. Lee Schwamm, director of the Center for TeleHealth at MGH and vice president of virtual care at Mass General Brigham.

Yes, but only under very unusual circumstances. Unless you have a rare inherited heart condition, consider these examples as curiosities rather than cause for concern.

If you take a statin, you've probably noticed the bright yellow sticker on the back of the prescription bottle warning you to avoid grapefruit and grapefruit juice. This tangy citrus fruit contains compounds that interfere with enzymes that break down various medications, including statins. This can boost blood levels of the drug, which could increase the risk of side effects.

It turns out that grapefruit also contains a substance called naringenin that can cause subtle changes in the heart's carefully choreographed timing. It does this by slightly prolonging what's known as the QT interval (see "What is long QT syndrome?"). To be clear, this phenomenon only happened in some volunteers after they drank about four cups of grapefruit juice. But a handful of other substances can have a similar effect, as described in an article about these so-called arrhythmogenic foods in the July 2020 issue of Trends in Cardiovascular Medicine.

Many provide links to published research about these heart -protecting drugs. Others mention personal beliefs about statins, some of which are inaccurate.

Statins are among the most frequently prescribed medications in the United States. These cholesterol-lowering drugs help reduce the risk of heart attacks and strokes, especially for people who've already had one of those life-threatening events. But many people stop taking their statins or don't take them as prescribed, a phenomenon doctors refer to as nonadherence.

Hoping to gain some insight into this trend, researchers analyzed 11,852 posts that mentioned statins on Twitter over a five-year period. About a quarter of Americans use Twitter, which is one of the most popular social media platforms. Although many of the tweets featured ads or financial market information, nearly half were related to health issues associated with statins. Of these, more than a third provided resource information, such as a link to a published study. About 20% included personal beliefs or attitudes about statins, which proved to be quite polarized. Some people described statins as lifesaving, while others referred to them as poisonous or deadly, according to the researchers, whose study was published June 25, 2020, in JAMA Network Open.