Medical Tests & Procedures Archive

Articles

Let's not call it cancer

Roughly one in six men will be diagnosed with prostate cancer at some point in their lives, but these cancers usually aren't life-threatening. The least risky form of the disease occurs frequently with age, will not metastasize to other parts of the body, and it doesn't require any immediate treatment. So, should it even be called cancer?

A liquid biopsy for metastatic prostate cancer

Researchers are developing tools for predicting how fast prostate cancer might progress; among the most promising are those that count circulating tumor cells (CTCs) in blood samples. Research shows that high CTC counts predict poorer survival and faster disease progression. But they are also predictive for early-stage metastatic prostate cancer that still responds to hormonal therapy.

Pap smears or self-swabs?

Pap tests, the mainstay screening method to detect cervical cancer, are uncomfortable for some women. In mid-2024, the FDA approved a new self-swab test that can detect human papillomavirus, which causes most cases of cervical cancer. The self-swab test collects cells from the vaginal wall instead of the cervix. Clinicians guide women on how to perform the test in a doctor's office. The self-swab method offers women several benefits, including comfort, accuracy, and potentially greater access to screening.

Transperineal prostate biopsies linked with lower infection risk

In a 2024 study, transperineal prostate biopsies were less likely to cause infections than traditional transrectal biopsies. Transperineal biopsies retrieve tissue samples using a thin needle inserted through the skin between the scrotum and rectum.

Could imaging scans replace biopsies during prostate cancer screening?

Abnormal results on a prostate-specific antigen (PSA) screening test for cancer are typically followed by a systematic biopsy. But systematic biopsies can be problematic, and researchers are seeking alternatives. A large European study provides encouraging evidence favoring a different approach that uses MRI instead of biopsy.

Keeping score of prostate cancer

Men with high prostate-specific antigen (PSA) levels often get a biopsy of prostate tissue to check for cancer. The results of the biopsy are calculated to create a Gleason score, which helps doctors assess whether the cancer is low-, medium-, or high-risk. Based on that information, doctors may recommend that a man follow active surveillance (in which he monitors his PSA for changes) or begin cancer treatment.

New guidelines released for vitamin D testing and supplementation

Updated guidelines say adults don't need routine testing of vitamin D levels. However, they should aim for daily vitamin D intake of 600 international units (IU) until age 70, and 800 IU after that either through vitamin D–fortified foods or a supplement of up to 1,000 IU.

FDA approves blood test for colorectal cancer screening

In 2024, the FDA approved a blood test called Shield as a screening method for colorectal cancer. The test detects 83% of colorectal cancers, but only 13% of precancerous polyps. The FDA approval means that now many insurance plans will pay for the test.

Is a reliable blood test for Alzheimer's disease finally here?

A study published in JAMA in July 2024 found that a blood test was accurate in diagnosing Alzheimer's disease, which causes steep declines in cognition and other aspects of health. The blood test is able to detect elevated blood levels of brain proteins that characterize the condition. While that's progress, doctors say it's not the test needed most. It would be more beneficial, they say, to have a test that accurately spots the developing disease long before it affects thinking. No such tests are here yet, but scientists are working to develop them.

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