Medical Tests & Procedures Archive

Leg pain may be caused by deep-vein thrombosis (DVT), a blood clot that forms in a deep vein, usually in the leg. Left untreated, the clot may break off, travel to the lungs, and cause blockage in a lung artery, known as pulmonary embolism (PE), which can be life threatening. Diagnosis of DVT and PE may include a review of symptoms, a D-dimer blood test, a leg ultrasound, or a chest CT scan. Both conditions are most often treated with direct-acting oral anticoagulants.

The approach to certain blood tests appears to be shifting. Doctors might stop ordering routine vitamin D screenings for healthy people younger than 75; they might order a one-time combination of lipoprotein(a), C-reactive protein, and LDL (bad) cholesterol tests as a way to predict future heart problems; and they might rely less on standard ranges designated as "normal" in a complete blood count (CBC) test, and instead focus more on comparing someone's latest CBC results to previous CBC tests.

Most people don't need to fast before a lipid test because the difference between LDL cholesterol values when fasting or not fasting is very small. But people who have had high triglyceride levels should fast prior to the test.

People who follow a healthy lifestyle can still have the early stages of coronary artery disease (CAD), the most common type of heart disease. There are many ways people can find out if they have CAD. This includes paying attention to whether exercise causes discomfort, doing a 10-year heart risk assessment, and seeing their doctor for diagnostic testing, such as a coronary artery calcium scan, a resting electrocardiogram, a walking stress test, or an echocardiogram. A doctor uses this information to determine the best treatment path.

High levels of Lp(a)—a fatty particle similar to LDL cholesterol—may double or triple a person's risk of a heart attack. About one in five adults may have elevated levels, which also raises the risk of stroke and aortic stenosis. Unlike LDL, which rises with age and is influenced by diet and exercise, Lp(a) remains largely constant over a person's lifetime, so a one-time test suffices for screening. Lp(a) testing is becoming more common now that five promising new Lp(a) therapies are in development.

After a heart attack or stent placement, people typically take a combination of aspirin and another antiplatelet drug. After one year, the new standard practice is to stop the aspirin, in contrast to the previous practice of stopping the other drug.

Roughly one in six men will be diagnosed with prostate cancer at some point in their lives, but these cancers usually aren't life-threatening. The least risky form of the disease occurs frequently with age, will not metastasize to other parts of the body, and it doesn't require any immediate treatment. So, should it even be called cancer?

Researchers are developing tools for predicting how fast prostate cancer might progress; among the most promising are those that count circulating tumor cells (CTCs) in blood samples. Research shows that high CTC counts predict poorer survival and faster disease progression. But they are also predictive for early-stage metastatic prostate cancer that still responds to hormonal therapy.

Pap tests, the mainstay screening method to detect cervical cancer, are uncomfortable for some women. In mid-2024, the FDA approved a new self-swab test that can detect human papillomavirus, which causes most cases of cervical cancer. The self-swab test collects cells from the vaginal wall instead of the cervix. Clinicians guide women on how to perform the test in a doctor's office. The self-swab method offers women several benefits, including comfort, accuracy, and potentially greater access to screening.