Medications Archive

Elevated LDL cholesterol contributes to cardiovascular disease. Taking statin drugs can substantially lower this risk. But what if a person's LDL level remains too high on their maximally tolerated dose? An expert consensus report lays out a clear path for next steps.

In recent years, treatment options for inflammatory bowel disease have expanded rapidly, with new types of drugs, new medications within existing classes, and new combinations of treatments for some patients.

Certain medications are safer and more effective than others for treating spine pain in older adults, according to a recent study. Among these are the over-the-counter drugs acetaminophen (Tylenol) and ibuprofen (Advil) and some nerve pain drugs, muscle relaxants, and antidepressants.

Everyone experiences acute (short-term) diarrhea at some time. The unpleasant experience often resolves on its own in a few days, but there are situations that require medical attention. Examples include bloody diarrhea, severe abdominal pain, a high fever, and episodes that continue for a week or longer. A medical consultation can help determine if diarrhea is related to a specific bacterium or parasite, a medication side effect, a food intolerance, or an inflammatory bowel disease.

Men often have a hard time coping with incontinence (urine leakage). It can leave them feeling depressed or socially isolated. Types of leakage problems in men include urge, stress, and overflow incontinence. Treatment depends on the type of incontinence a man is experiencing. For example, overflow incontinence may get better with a procedure to reduce the size of the prostate; medications, injections in the bladder muscle, and pelvic floor exercises can help with urge incontinence.

After surgery unrelated to the heart, a diagnosis of atrial fibrillation (afib) may be more common than previously thought. These cases, which may constitute 13% of new afib diagnoses, appear to be undertreated.

Anti-clotting medications have a well-known and fairly common effect: a heightened risk of bleeding. Being older, having certain health conditions, and taking certain drugs (including popular over-the-counter pain relievers) can increase this risk. Minor bleeding includes bleeding gums after toothbrushing or flossing and nosebleeds that take longer than usual to stop. Signs of more serious bleeding (which requires immediate medical care) include tea-colored, pink, or red urine; blood in the stool or black, tarry stools; or a sudden, severe headache.

Vascular dementia, which arises from longstanding, cumulative damage to small blood vessels in the brain, may cause or contribute to up to half of cases of dementia. The vessels may thicken or become blocked by blood clots, causing tiny strokes that damage specific parts of the brain important for various thinking abilities. Keeping blood pressure in the recommended range of 120/80 or lower is the best way to prevent vascular dementia.

Renewed research into the potential benefits of psychedelic drugs has led to interest in microdosing — taking a fraction of a regular dose. Many people believe that microdosing can help them, but the evidence from some recent studies is mixed.

Proton-pump inhibitors are a commonly prescribed anti-acid medication, but new guidelines from the American Gastroenterological Association recommend that they should be taken at the lowest dose and shortest duration for the condition being treated.