Medications Archive

Many of my patients, colleagues, friends, and even neighbors have asked me about the new drug flibanserin (Addyi), which the FDA recently approved for treatment of low sexual desire in women. Flibanserin has generated more questions, comments, and media inquiries for me than I've ever experienced in my 20-year career as an obstetrician/gynecologist. While there are several medications that improve sexual function in men (including Viagra, the most famous one), flibanserin is the first to be approved for that purpose in women. Here are what I consider the relevant facts about flibanserin, and what I say to my patients.

These potent medications are for hard-to-manage cases of high cholesterol—not replacements for the tried-and-true statins.

For optimal results, you need to take your medication regularly and time it correctly to your meals.

Have you tried to cool the burning discomfort of heartburn with medication and failed to get full relief? If so, a few simple adjustments to optimize your treatment may be all you need.

Be on the lookout for mood swings, sleeplessness, and anxiety when starting certain medications.

The medications your doctor prescribes may depend on your underlying health issues.

New warnings suggest that even people without heart problems may be at risk for heart attack and stroke with NSAID use.

Q. My doctor used to check my liver function once a year after I started taking a statin drug to lower my cholesterol, but he doesn't anymore. Why not?

A. Your doctor appears to be following the latest recommendations from the American Heart Association and the FDA. When statin medications were first approved, doctors did periodic blood tests to check for liver injury. Three decades later, it is clear that serious liver injury from statins is a rare side effect and that routine blood testing does not help identify people at risk for statin-related liver problems. Therefore, routine monitoring is not a good use of money and time.

But if you are healthy, deciding if these commonly prescribed drugs are right for you is a personal choice.

NSAID users: Take the lowest effective dose for the shortest possible time.

If you have heart disease, national guidelines recommend that you take a low-dose (81-mg) aspirin every day. It's an inexpensive and effective way to lower your risk of a heart attack or stroke. According to a report in the July 17 Morbidity and Mortality Weekly Report, about seven in 10 adults with heart disease follow this advice.

The study relied on telephone surveys done by the CDC about health behaviors. It included data from more than 17,900 adults from 20 states and the District of Columbia.