Mind & Mood Archive

The daily onslaught of news during the past year has left many people in a steady state of fatigue, resignation, and grief. The symptoms of collective trauma are widespread and familiar, but one merits special attention: numbness, which is one possible response to an overwhelming situation.

Two common classes of drugs have been linked to dementia. Fortunately, there are alternatives to both.

If you're worried about developing dementia, you've probably memorized the list of things you should do to minimize your risk—eating a healthy diet, exercising regularly, getting adequate sleep, and keeping your mind and soul engaged. In addition, some of the drugs you may be taking to help you accomplish those things could increase your risk of dementia. In two separate large population studies, both benzodiazepines (a category that includes medications for anxiety and sleeping pills) and anticholinergics (a group that encompasses medications for allergies and colds, depression, high blood pressure, and incontinence) were associated with an increased risk of dementia in people who used them for longer than a few months. In both cases, the effect increased with the dose of the drug and the duration of use.

These findings didn't come entirely as a surprise to doctors who treat older people. The Beer's List published by the American Geriatrics Society has long recognized benzodiazepines, antihistamines, and tricyclic antidepressants as potentially inappropriate for older adults, given their side effects. Such drugs are on the list because they share troubling side effects—confusion, clouded thinking, and memory lapses—that can lead to falls, fractures, and auto accidents.

Too much time together makes for tense moments. Cutting each other some slack and setting ground rules will help.

There's such a thing as too much togetherness at home, no matter if you're with a romantic partner, an adult child, a grandchild, or a friend. "Because of the pandemic, we're frozen in place with people, but we aren't meant to be in the same space all day long," says Dr. Robert Waldinger, a psychiatrist with Harvard-affiliated Massachusetts General Hospital.

Keeping the peace starts with understanding why you may be getting on each other's nerves. Then you can try following a few rules to get along better.

In the journals

Flavanols give fruits and vegetables their bright colors. They are also found in tea and cocoa. Observational studies have shown that eating foods rich in flavanols is linked with less cognitive decline as people age. New research suggests a possible reason why: flavanols appear to improve blood flow to the brain.

Researchers gave cocoa flavanols to 18 healthy adults in two separate trials. In one, the people consumed a cocoa drink with about 681 milligrams (mg) of flavanols. In the other, they had a cocoa drink with about 4 mg of flavanols. About two hours after having the cocoa drink, participants briefly inhaled air with high concentrations of carbon dioxide to raise their blood level above normal. (The brain's normal response to high blood carbon dioxide levels is to increase both blood flow to the brain and its uptake of oxygen.) The researchers then measured the speed of brain oxygenation and administered a set of mental tasks to assess cognitive performance. People had a faster brain oxygenation response after consuming high amounts of flavanols compared with lower amounts. They also scored higher on the cognitive tests and correctly solved problems 11% quicker.

Empathy helps people get along with others, but the ability to understand another person’s experience comes more easily to some people than to others. However, the capacity for empathy can be honed and improved like any other skill.

The deaths of friends and family members become more common as you age. Here is how to endure the grieving process.

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Most men don't face much personal loss early in their lives. Yet, once they reach a certain age, they will encounter the experience of losing someone important to them — a spouse, a friend, a relative — and the feelings of grief that often follow.

"Grief is a natural response to loss, but it is something that men are not prepared for, and they often struggle to understand how it can affect their lives," says Dr. Eric Bui, associate director for research at the Center for Anxiety and Traumatic Stress Disorders and Complicated Grief Program at Harvard-affiliated Massachusetts General Hospital.

Here's what the research says about diet and depression.

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If you've ever found yourself in front of the TV after a bad day, mindlessly digging ice cream out of the container with a spoon, you know that mood and food are sometimes linked. But while stress eating is a verified phenomenon, the relationship between food and actual mood disorders, such as depression, is less clear. Or, to put it another way: can the things you eat influence your risk for depression — and can dietary changes potentially improve your mental health?

"The research regarding dietary factors and depression is still inconclusive," says Patricia Chocano-Bedoya, a visiting scientist in the Department of Nutrition at the Harvard T.H. Chan School of Public Health. But there have been hints that food may play a role in depression.

Stress management may reduce health problems linked to stress, which include cognitive problems and a higher risk for Alzheimer's disease and dementia.

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It's not uncommon to feel disorganized and forgetful when you're under a lot of stress. But over the long term, stress may actually change your brain in ways that affect your memory.

Studies in both animals and people show pretty clearly that stress can affect how the brain functions, says Dr. Kerry Ressler, chief scientific officer at McLean Hospital and professor of psychiatry at Harvard Medical School. Scientists have seen changes in how the brain processes information when people experience either real-life stress or stress manufactured in a research setting. (For the latter, researchers might challenge subjects to perform a difficult task, such as counting backward from the number 1,073 by 13s while being graded.) Either type of stress seems to interfere with cognition, attention, and memory, he says.

So how do you keep your brain healthy, stay cognitively fit, and build your cognitive reserve? It's easier for some people than for others. And though genetics set the stage for your brain health, you can do something to improve your brain health and cognitive fitness.

First it is important to remember that you need a healthy body to have a healthy brain. Therefore, ensuring your brain health depends upon regularly seeing your doctor, following her or his recommendations, and managing any health conditions you have.

A regular practice can help your brain better manage stress and anxiety that can trigger depression.

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Depression continues to be a major health issue for older adults. It affects about 20% of adults ages 65 and older, and regular depression can lead to higher risks for heart disease and death from illnesses. It also affects people's daily lives by making them more socially isolated and affecting cognitive function, especially memory.

In fact, a study of 1,111 people (average age 71), published online May 9, 2018, by Neurology, found that those who had greater symptoms of depression also had worse episodic memory — the ability to recall specific experiences and events.