Staying Healthy Archive

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Why did the FDA issue a fecal transplant warning?

Ask the doctors

Q. I heard that the FDA recently issued a warning related to a specific treatment for Clostridium difficile infections. Can you explain what this warning is about?

A. The FDA issued a warning in June aimed at health care providers who are using fecal transplants to treat Clostridium difficile (C. difficile) infections that have not responded to traditional treatments, such as antibiotics. Doctors perform fecal transplants (which are still considered investigational by the FDA) by introducing stool from a healthy donor into the gastrointestinal tract of the person infected with C. difficile. The introduction of healthful bacteria can sometimes treat the infection, which typically inflames the colon causing symptoms such as severe diarrhea, cramps, and fever. The FDA issued its warning after two immunocompromised adults developed infections from an antibiotic-resistant strain of Escherichia coli (E. coli) following transplants from stool contaminated with the bacteria. Both people got transplants from the same donor. One of the two people died following the infection. To prevent similar problems in the future, the FDA now recommends that doctors performing these transplants follow some new safety measures, including the following:

Red meat, TMAO, and your heart

A substance called trimethylamine N-oxide, which is produced when your body digests red meat, may raise the risk of cardiovascular problems.

Experts used to think that red meat raised your risk of heart disease simply because it was high in saturated fat. But today that picture has gotten more complicated thanks to the discovery of a metabolite — a substance produced during digestion and metabolism — called trimethylamine N-oxide, or TMAO.

According to a news article published June 11 in JAMA, three recent analyses have linked high blood levels of TMAO with a higher risk for both cardiovascular disease and early death from any cause. In one of those studies, researchers found that people with higher levels of TMAO in their blood may have more than twice the risk of heart attack, stroke, or other serious cardiovascular problems, compared with people who have lower levels. Other studies have found links between high TMAO levels and heart failure and chronic kidney disease.

Don’t forget your feet

Women sometimes neglect their feet until they start to experience foot pain and other problems.

Most women get their teeth cleaned at least once a year, keep tabs on their heart, and may even have an annual eye exam. While they might clip and paint their toenails on a regular basis, women often neglect the health of their feet.

That lack of attention can lead to pain and other foot problems, which are common and — for some people — life-altering.

Artificial light at night may lead to weight gain

Research we're watching

If you leave lights shining or keep the television on while you sleep, it could affect your waistline, according to a study published online June 10 by JAMA Internal Medicine. The study found an association between exposure to artificial light during sleep and weight gain in women.

The research team looked at questionnaires completed by more than 40,000 women, which asked, among other things, whether the women slept with lights on nearby or in the same room. The researchers also recorded the women's height, body mass index (a measure of weight in relation to height), and waist size at the time they entered the study and then five years later. They found that women who slept with a light or television on in the room were 17% more likely to have gained 11 pounds or more during the course of the study. They did not find a similar effect when women used a small night light or had a light on outside the room that shone in. It's not clear why exposure to artificial light was linked with weight gain, but researchers speculated that it might affect sleep quality.

Talking to your doctor about your LGBTQ+ sex life

Talking about sexuality with a doctor can be uncomfortable. If you identify as LGBTQ+, it's important to find a doctor who is attuned to the specific needs of the LGBTQ+ community. This can make getting proper care easier.

Do employee wellness programs actually work?

Do employee health programs lead to healthier, more productive employees? A large study shows little or no impact, although results might vary based on workplace, offerings, and other factors.

How much sleep do we really need?

Ask the doctor

Q. How much sleep do we really need, and what happens if we get too little or too much?

A. We spend about a third of our lives sleeping, so you've asked an important question.

Maximizing home food delivery

Take advantage of the many delivery options to keep your diet fresh, healthy, and full of variety.

Getting groceries or prepared meals without leaving your couch is easier than ever in this era of home delivery. That's important for people who have difficulty getting to the grocery store because they don't drive or because they're struggling with a chronic condition.

But the many options for food delivery may have you wondering where to begin. Here's a look at some widely used services and what to keep in mind when you use them.

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