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What can you do to avoid Alzheimer’s disease?

How a healthy lifestyle can make a difference in Alzheimer’s prevention.

Alzheimer's disease, the most common form of dementia, is characterized by the accumulation of two types of protein in the brain: tangles (tau) and plaques (amyloid-beta). Eventually, Alzheimer's kills brain cells and takes people's lives.

Alzheimer’s causes

What causes Alzheimer's? We still aren't sure. "For 1% of all cases, there are three genes that determine definitively whether or not you will have Alzheimer's, and all three relate to amyloid-beta production, which in these cases is likely the cause of Alzheimer's," says Dr. Gad Marshall, associate medical director of clinical trials at the Center for Alzheimer Research and Treatment at Harvard-affiliated Brigham and Women's Hospital. "For the other 99%, amyloid and tau are closely associated with Alzheimer's, but many things may contribute to the development of symptoms, such as inflammation in the brain, vascular risk factors, and lifestyle."

What to do when your medication causes nausea

Taking your pills with a light snack or at bedtime may help reduce the nausea.

You take medication hoping it will make you feel better. But sometimes it makes you feel worse. "Nausea is one of the most common side effects of medications we hear about," says Joanne Doyle Petrongolo, a pharmacist at Harvard-affiliated Massachusetts General Hospital.

About nausea

Nausea is a queasy feeling in your stomach — you may feel seasick, or you may feel you're about to vomit. Medications that commonly cause nausea as a side effect include antibiotics, such as erythromycin (Erythrocin); aspirin; nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen (Advil, Motrin) or naproxen (Aleve); and some blood pressure drugs, such as the calcium-channel blocker nifedipine (Nifedical, Procardia).

Are you tired from...too much sleep?

A bad night's sleep can leave you feeling pretty tired the next day. Put a string of those together and nagging fatigue starts to set in.

Getting good sleep, in the right amount, can make a big difference in how you feel. Too little or too much sleep can increase your perception of fatigue. And even if you get enough hours of sleep, you might find yourself dragging the next day if that sleep was interrupted by frequent awakenings or was of poor quality.

Why not flaxseed oil?

There's no mercury to worry about, and flaxseed oil  does contain omega-3 fats...but not the best kind.

Troll the medical literature, and you'll come up with study after study showing that fish and fish oil are good for us, especially for our hearts but maybe also for our moods and immune systems. Various epidemiologic investigations have found that people who eat fish regularly are less likely to have heart attacks, suffer strokes, or die from sudden cardiac arrest. The definition of "regularly" varies, but it usually means at least a couple of times a week, although eating fish even once a month has been shown to make a difference.

Fish, and especially fish oil, have also been the subject of dozens of randomized clinical trials, most involving people with existing heart conditions. In large amounts (several grams a day), fish oil has been shown to nudge various cardiac risk factors ("good" HDL cholesterol, triglycerides, blood pressure) in the right direction.

When someone you love won’t create an advance directive

What if someone you love doesn't have an advance directive? That's common, although the underlying reasons may differ. Basic barriers include thinking that an advance directive isn't needed, not wanting to think about death or serious illness, not wanting to burden people, not knowing enough about advance directives and health care choices, needing help to fill out the forms, and lack of time with the doctor to discuss the matter. A person's ethnic or cultural background can also be a barrier: minorities tend to be more suspicious of health care providers and resistant to talking about or completing advance directives. According to AARP, African Americans in home health care and nursing homes are half as likely as whites to have advance directives.

To deal with this situation, try asking your loved one two simple questions, even if you think you know the answers.

The doctor will see you now, in your home

The old-fashioned house call is back in a big way. Here's how it works.

It's hard to get to the doctor when you don't drive anymore or you're struggling with several chronic medical conditions. The result may be missed appointments and a lack of needed care.

But a growing trend makes it far easier for older adults to get medical attention, bringing routine exams and diagnostic tests to the patient's doorstep. It's called home-based medical care — when doctors, nurse practitioners, physician assistants, or other providers visit and treat older adults right in their homes.

Dive into a swimming regimen

Lap swimming offers a total-body workout of strengthening, stretching, and aerobic conditioning.

When you think of a swimming workout, you may envision an athlete pounding away at the water, racing from one end of the pool to the other. But you don't have to break speed records to reap the rewards of swimming back and forth, and you don't even have to do the competitive swimming stroke known as the crawl.

"The pace is up to you, and any stroke is fine. Breaststroke, sidestroke, and backstroke are often favored because a lot of people don't like putting their face in the water, like you have to do with the crawl," says Leigh de Chaves, a physical therapist and clinical supervisor of rehabilitation services at Harvard-affiliated Brigham and Women's Hospital. She also swam competitively in college.

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