Staying Healthy Archive

Research we're watching

While opioid use disorders have gotten a lot of attention in recent years, the number of people dying as a result of methamphetamine use is on the rise. A study published Jan. 14, 2021, in The New England Journal of Medicine found that a combination drug therapy may provide some hope in helping people with this difficult-to-treat disorder.

In the trial, half of the 403 adult volunteers were given a combination of two drugs: naltrexone, which is used to treat both opioid and alcohol use disorders, and bupropion, an antidepressant. The other half of the group received a placebo. The treatment period began in 2017 and ended in 2019. During that time people were given periodic urine tests to gauge whether they used methamphetamines. Those who had at least three of four drug-free tests were defined as having responded to treatment. Researchers found that by weeks five and six, 16.5% of the treatment group had responded to treatment, compared with 3.4% of the control group. By weeks 11 and 12, 11.4% of the treatment group met the urine test criteria for successful treatment, compared with less than 2% of the control group. Most people who received the drug treatment didn't have any serious side effects.

Smaller sizes and high-tech placement methods mean more people are candidates for prosthetic teeth.

If you've been told you're not a candidate for dental implants, it's time to revisit the subject. Dental implants — permanent prosthetics implanted into the jaw — have changed.

"In the last five years, we've learned that smaller implants can work just as well as regular-size implants, and this makes more people candidates for them," says Dr. German Gallucci, department chair of restorative dentistry at the Harvard School of Dental Medicine.

Strengthening your core will rev up your balance and stability.

After a long winter with lots of isolating and maybe too little physical activity, it might be time to give your core muscles more attention.

These muscles, located throughout much of your trunk, are the key to supporting your lower back and helping you stand, get out of a chair, bend, lift, and maintain your balance. So regular maintenance and tune-ups of the core muscles are important.

News briefs

Living a healthy lifestyle may be one of the best things you can do to tame the heartburn of gastroesophageal reflux disease (GERD), suggests a research letter published online Jan. 4, 2021, by JAMA Internal Medicine. Harvard researchers analyzed the self-reported health information of about 43,000 middle-aged women who were followed for 10 years. Women who adhered to five healthy lifestyle factors, regardless of whether they took heartburn medication, appeared to prevent nearly 40% of their GERD symptoms each week. The pill-free approaches included maintaining a healthy body weight (a body mass index between 18.5 and 24.9); not smoking; getting 30 minutes daily of moderate-to-vigorous physical activity; limiting coffee, tea, or soda to no more than 2 cups per day; and eating a healthy diet. "Each one of these factors may prevent the inappropriate relaxation of the sphincter muscle between the stomach and the esophagus, helping to keep acid from refluxing up and causing heartburn. For example, carrying extra weight around the waist can push on the stomach, forcing stomach acid up into the esophagus," says Dr. Raaj S. Mehta, lead author of the study and a gastroenterology fellow at Harvard-affiliated Massachusetts General Hospital.

Image: © kate_sept2004/Getty Images

Rapidly becoming a racquet sport favorite, pickleball serves up various physical, mental, and social benefits.

You keep hearing that older adults need to stay active physically, mentally, and socially. But what if you could do all three at once? You can if you play the racquet sport pickleball, one of the country's fastest-growing forms of recreation.

"In many ways, pickleball is the ideal activity for older adults," says Timothy Rivotto, a physical therapist and tennis coach with Harvard-affiliated Spaulding Rehabilitation Network. "It can accommodate people with different fitness levels and still offer a good aerobic workout. Pickleball also requires using key brain skills and is an exciting way to interact with others."

In the journals

Regular exercise is good medicine, but more may be better, suggests a study published online Jan. 12, 2021, by PLOS Medicine. Scientists asked more than 90,000 people without heart disease to wear a fitness tracker for a week to measure the duration and intensity of their physical activity. Five years later, they found that the most active people were less likely to have had a heart attack or stroke or be diagnosed with heart disease.

That's no surprise, but the researchers also discovered that risk continued to shrink as weekly minutes of activity and intensity rose. People who exercised the most and at the highest intensity had the best odds of maintaining good cardiovascular health. Guidelines recommend people get 150 to 300 minutes of moderate-intensity exercise per week, but these findings suggest that trying to do a little extra — whether in time, intensity, or both — offers more reward.

In the journals

Blood pressure readings are usually done on only one arm, but a new analysis makes the case for checking both arms, as the difference between them may suggest an elevated risk for heart disease. The findings were published in the February 2021 issue of Hypertension.

Researchers examined 24 studies that measured blood pressure in both arms in 53,827 adults without high blood pressure. They found that a difference of more than five points between the left and right arm systolic readings (the top number) was linked with a 9% higher risk for a first-time heart attack or stroke and a 6% increase in cardiovascular death within 10 years. The greater the difference between the two readings, the higher the risk.

Ask the doctors

Q. I experienced a heart attack a few years ago. I'm worried about getting the COVID-19 vaccine. Is it safe for someone with my medical history?

A. Yes. The vaccine is safe and advised for people with a history of heart attack and cardiovascular disease. While you should always discuss the particulars of your situation with your doctor, the American Heart Association said in a statement issued on Jan. 15, 2021, that it's important for people who have had heart disease or stroke (or who are at high risk for these conditions) to get vaccinated as quickly as possible, because they are at higher risk for severe disease if infected. The benefits of the vaccine far outweigh the risks. Clinical trials of the first two approved vaccines found that both are safe and, after two injections, are about 95% effective at preventing illness from SARS-CoV-2, the virus that causes COVID-19. The vaccine often causes soreness at the injection site. Other common side effects, such as headache and diffuse muscle pain, are usually mild and last only one or two days. More severe reactions, including allergic reactions, have occurred but are very rare.

Among the Basic Practice exercises in "Intermediate Yoga," a special health report from Harvard Medical School, is this breathing exercise. "Three-part breath" is simple enough to do almost anytime and anywhere. To learn additional intermediate yoga exercises, visit: www.health.harvard.edu/iy

"Half sun salutation" is among the Basic Practice exercises described in "Intermediate Yoga," a special health report from Harvard Medical School. To learn additional intermediate yoga exercises, visit: www.health.harvard.edu/iy