Vaccinations Archive

Research we're watching

A long-used vaccine is showing promise in helping to restore near-normal blood sugar levels in people with advanced type 1 diabetes. Researchers from Harvard Medical School injected adults who had type 1 diabetes with two doses of the bacillus Calmette-Guérin (BCG) vaccine, which is traditionally used to prevent tuberculosis.

Participants in the study, all of whom had type 1 diabetes for many years, all showed significant improvements in their average blood sugar levels after the vaccination. The improvements lasted for the next five years. Researchers said that it appears the vaccine affected a metabolic mechanism that increases consumption of glucose by cells.

News briefs

Baby boomers are falling short in getting hepatitis C screenings. In 2012, the CDC urged the entire generation of people born from 1945 to 1965 to get this simple blood test, noting that baby boomers are five times more likely to have the virus than other adults. But a study published online March 27, 2018, by the journal Cancer Epidemiology, Biomarkers & Prevention found that only about 13% of baby boomers had been tested by 2015, up just one percentage point from 2013. The information came from national government health surveys. Hepatitis C can lead to cirrhosis, liver damage, liver cancer, and liver failure. Treatments are now available that can cure hepatitis C, if it's caught early enough. Baby boomers are believed typically to have become infected in the 1960s through the 1980s, when transmission of hepatitis C was highest. People at highest risk are those who have used intravenous drugs, had more than one sex partner, or received a blood transfusion before 1992, when the blood test for hepatitis C was first available.

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On call

Q. There has been a lot of talk about the severity of this flu season, and I recently heard that influenza also can trigger a heart attack. Should I worry?

A. Influenza is responsible for about 10,000 to 20,000 annual deaths, mostly from pneumonia or internal organ failure. In other situations, influenza infection strains a person's health, which can worsen underlying conditions, such as heart disease.

Research we're watching

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If you have an egg allergy, you may have been told not to get a flu shot. That's because the vaccine is grown in eggs and may contain a small amount of egg protein, which — it was feared — could trigger an allergic reaction. But a new guideline from the American College of Allergy, Asthma and Immunology (ACAAI) dispenses with that old advice and says even people with an egg allergy should roll up their sleeves and get the shot to protect themselves from the flu.

"When people get flu shots, health care providers often ask if they are allergic to eggs," allergist Dr. Matthew Greenhawt, chair of the ACAAI Food Allergy Committee and lead author of the practice parameter, said in a written release. "We want health care providers and people with egg allergy to know there is no need to ask this question anymore, and no need to take any special precautions. The overwhelming evidence since 2011 has shown that a flu shot poses no greater risk to those with egg allergy than those without." Numerous studies have found that patients with egg allergy — even those with life-threatening allergies to egg — have gotten the shot and did not suffer any ill effects. This suggests there isn't enough egg protein in the vaccine to cause a reaction.