Vitamins & Supplements Archive

Ten years of data suggest that AREDS2 supplements are associated with a reduced risk of macular degeneration progression without any increase in lung cancer risk, according to a follow-up study published online June 2, 2022, by JAMA Ophthalmology.

An estimated 3.2% of adults ages 50 or older have very low B₁₂ levels, and up to 20% may have borderline deficiency. Aging is often the cause. Other causes include taking heartburn medications; eating a diet that does not include animal products; weight loss surgery; or autoimmune diseases that attack the stomach lining or gastrointestinal tract. It’s a good idea for older adults to take a B₁₂ supplement of 2.8 micrograms daily to ward off B₁₂ deficiency. People who have very low levels of B₁₂ may need to take a much higher dose or get B₁₂ injections.

One in three Americans takes a daily multivitamin even though research shows this doesn't provide any meaningful health benefits for most people. And because of the way supplements are regulated, some supplements make claims that have no evidence behind them.

Nutrient deficiencies are uncommon with a broad and varied diet. But aging, hormonal factors, or diet can leave women short of four key vitamins and minerals: vitamin D, iron, vitamin B₁₂, and calcium. Various tests can reveal nutrient deficiencies, including blood panels. Vitamin D and fish oil supplements may help prevent autoimmune diseases. Multivitamins are usually unnecessary, except in cases where age, pregnancy, digestive challenges, or certain medications interfere with the ability to get adequate nutrition.

The number of people taking large amounts of melatonin (more than 5 milligrams per day) is at an all-time high. However, the amount in a supplement can be significantly higher than what the label shows. This can cause people to take too much, especially since many use melatonin regularly.

Taking a multivitamin does not reduce the chance of heart disease or mental decline, but it does reduce the risk of being diagnosed with cancer or developing cataracts.

Sleep supplements, such as cannabidiol (CBD), melatonin, valerian, and chamomile promise a better night's sleep. But there is little evidence showing that they are effective. In addition, supplements aren't regulated, so it's not always clear if a formula contains what's listed on the label. Experts say that behavioral strategies are a better way to improve sleep. These include getting more exercise, going to bed and waking up at the same time each day, and sleeping in a cool, dark room.